There are
376 mi
from Mckeesport, PA to Seymour, IN
That's the driving distance. It would take 7 hours 44 mins to go from Mckeesport, Pennsylvania to Seymour, Indiana.
The flight distance (direct flight from Mckeesport, PA to Seymour, IN) is 334.53 mi.
376 mi = 605.02 kms