There are
589 mi
from Mckeesport, PA to Edwardsville, IL
That's the driving distance. It would take 11 hours 20 mins to go from Mckeesport, Pennsylvania to Edwardsville, Illinois.
The flight distance (direct flight from Mckeesport, PA to Edwardsville, IL) is 547.33 mi.
589 mi = 948.27 kms