There are
2,124 mi
from Mcallen, TX to Holyoke, MA
That's the driving distance. It would take 1 day 16 hours to go from Mcallen, Texas to Holyoke, Massachusetts.
The flight distance (direct flight from Mcallen, TX to Holyoke, MA) is 1,822 mi.
2,124 mi = 3.22 kms