There are
436 mi
from Marietta, GA to Cape Girardeau, MO
That's the driving distance. It would take 8 hours 26 mins to go from Marietta, Georgia to Cape Girardeau, Missouri.
The flight distance (direct flight from Marietta, GA to Cape Girardeau, MO) is 362.57 mi.
436 mi = 701.27 kms