There are
1,533 mi
from Manchester, NH to South Sioux City, NE
That's the driving distance. It would take 1 day 4 hours to go from Manchester, New Hampshire to South Sioux City, Nebraska.
The flight distance (direct flight from Manchester, NH to South Sioux City, NE) is 1,262.51 mi.
1,533 mi = 1.61 kms