There are
3,046 mi
from Lowell, MA to Seatac, WA
That's the driving distance. It would take 2 days 6 hours to go from Lowell, Massachusetts to Seatac, Washington.
The flight distance (direct flight from Lowell, MA to Seatac, WA) is 2,467.05 mi.
3,046 mi = 4,901.37 kms