There are
1,662 mi
from Lowell, MA to Lexington, NE
That's the driving distance. It would take 1 day 6 hours to go from Lowell, Massachusetts to Lexington, Nebraska.
The flight distance (direct flight from Lowell, MA to Lexington, NE) is 1,464.94 mi.
1,662 mi = 1.61 kms