There are
1,662 mi
from Lowell, MA to Guthrie, OK
That's the driving distance. It would take 1 day 7 hours to go from Lowell, Massachusetts to Guthrie, Oklahoma.
The flight distance (direct flight from Lowell, MA to Guthrie, OK) is 1,465.79 mi.
1,662 mi = 1.61 kms