There are
1,894 mi
from Lowell, MA to Brenham, TX
That's the driving distance. It would take 1 day 11 hours to go from Lowell, Massachusetts to Brenham, Texas.
The flight distance (direct flight from Lowell, MA to Brenham, TX) is 1,629.79 mi.
1,894 mi = 1.61 kms