Miles between Louisville, KY and Simpsonville, SC

There are
406 mi
from Louisville, KY to Simpsonville, SC

That's the driving distance. It would take 8 hours 15 mins to go from Louisville, Kentucky to Simpsonville, South Carolina.

The flight distance (direct flight from Louisville, KY to Simpsonville, SC) is 311.21 mi.

406 mi = 652.83 kms