Miles between Louisville, KY and Cape Girardeau, MO

There are
260 mi
from Louisville, KY to Cape Girardeau, MO

That's the driving distance. It would take 5 hours 7 mins to go from Louisville, Kentucky to Cape Girardeau, Missouri.

The flight distance (direct flight from Louisville, KY to Cape Girardeau, MO) is 215.47 mi.

260 mi = 417.70 kms