There are
361 mi
from Lexington, KY to Midlothian, IL
That's the driving distance. It would take 6 hours 50 mins to go from Lexington, Kentucky to Midlothian, Illinois.
The flight distance (direct flight from Lexington, KY to Midlothian, IL) is 300.65 mi.
361 mi = 580.73 kms