There are
350 mi
from Lexington, KY to Crestwood, MO
That's the driving distance. It would take 6 hours 32 mins to go from Lexington, Kentucky to Crestwood, Missouri.
The flight distance (direct flight from Lexington, KY to Crestwood, MO) is 320.67 mi.
350 mi = 562.75 kms