Miles between Lexington, KY and Cape Girardeau, MO

There are
325 mi
from Lexington, KY to Cape Girardeau, MO

That's the driving distance. It would take 6 hours 20 mins to go from Lexington, Kentucky to Cape Girardeau, Missouri.

The flight distance (direct flight from Lexington, KY to Cape Girardeau, MO) is 278.85 mi.

325 mi = 523.07 kms