There are
386 mi
from Lexington, KY to Ashtabula, OH
That's the driving distance. It would take 7 hours 26 mins to go from Lexington, Kentucky to Ashtabula, Ohio.
The flight distance (direct flight from Lexington, KY to Ashtabula, OH) is 329.35 mi.
386 mi = 621.12 kms