There are
746 mi
from Lawton, OK to Madisonville, KY
That's the driving distance. It would take 13 hours 47 mins to go from Lawton, Oklahoma to Madisonville, Kentucky.
The flight distance (direct flight from Lawton, OK to Madisonville, KY) is 637.35 mi.
746 mi = 1,200.13 kms