There are
1,740 mi
from Laurel, MS to Calexico, CA
That's the driving distance. It would take 1 day 6 hours to go from Laurel, Mississippi to Calexico, California.
The flight distance (direct flight from Laurel, MS to Calexico, CA) is 1,539.44 mi.
1,740 mi = 2,800.24 kms