There are
726 mi
from Las Cruces, NM to Upland, CA
That's the driving distance. It would take 12 hours 44 mins to go from Las Cruces, New Mexico to Upland, California.
The flight distance (direct flight from Las Cruces, NM to Upland, CA) is 640.73 mi.
726 mi = 1,168.53 kms