There are
1,144 mi
from Las Cruces, NM to Clayton, MO
That's the driving distance. It would take 21 hours 5 mins to go from Las Cruces, New Mexico to Clayton, Missouri.
The flight distance (direct flight from Las Cruces, NM to Clayton, MO) is 1,020.91 mi.
1,144 mi = 1.61 kms