Miles between Largo, FL and Hilton Head Island, SC

There are
385 mi
from Largo, FL to Hilton Head Island, SC

That's the driving distance. It would take 7 hours 33 mins to go from Largo, Florida to Hilton Head Island, South Carolina.

The flight distance (direct flight from Largo, FL to Hilton Head Island, SC) is 321.46 mi.

385 mi = 618.98 kms