There are
1,258 mi
from Laredo, TX to Sioux Falls, SD
That's the driving distance. It would take 22 hours 9 mins to go from Laredo, Texas to Sioux Falls, South Dakota.
The flight distance (direct flight from Laredo, TX to Sioux Falls, SD) is 1,119.50 mi.
1,258 mi = 1.61 kms