There are
1,404 mi
from Laredo, TX to Mesquite, NV
That's the driving distance. It would take 1 day 1 hour to go from Laredo, Texas to Mesquite, Nevada.
The flight distance (direct flight from Laredo, TX to Mesquite, NV) is 1,064.67 mi.
1,404 mi = 2,259.45 kms