There are
1,266 mi
from Laredo, TX to Jeffersonville, IN
That's the driving distance. It would take 22 hours 22 mins to go from Laredo, Texas to Jeffersonville, Indiana.
The flight distance (direct flight from Laredo, TX to Jeffersonville, IN) is 1,089.48 mi.
1,266 mi = 2,038.08 kms