There are
1,801 mi
from Laredo, TX to Depew, NY
That's the driving distance. It would take 1 day 8 hours to go from Laredo, Texas to Depew, New York.
The flight distance (direct flight from Laredo, TX to Depew, NY) is 1,576.97 mi.
1,801 mi = 1.61 kms