Miles between Lancaster, SC and Tupelo, MS

There are
529 mi
from Lancaster, SC to Tupelo, MS

That's the driving distance. It would take 10 hours 13 mins to go from Lancaster, South Carolina to Tupelo, Mississippi.

The flight distance (direct flight from Lancaster, SC to Tupelo, MS) is 452.76 mi.

529 mi = 851.92 kms