There are
2,521 mi
from Lancaster, CA to North Tonawanda, NY
That's the driving distance. It would take 1 day 20 hours to go from Lancaster, California to North Tonawanda, New York.
The flight distance (direct flight from Lancaster, CA to North Tonawanda, NY) is 2,169.60 mi.
2,521 mi = 3.22 kms