There are
1,277 mi
from Lakewood, CO to San Mateo, CA
That's the driving distance. It would take 22 hours 3 mins to go from Lakewood, Colorado to San Mateo, California.
The flight distance (direct flight from Lakewood, CO to San Mateo, CA) is 940.93 mi.
1,277 mi = 2,054.48 kms