There are
1,207 mi
from Lakewood, CO to Defiance, OH
That's the driving distance. It would take 21 hours 47 mins to go from Lakewood, Colorado to Defiance, Ohio.
The flight distance (direct flight from Lakewood, CO to Defiance, OH) is 1,091.81 mi.
1,207 mi = 1,942.75 kms