There are
2,304 mi
from Lakeland, FL to Mesquite, NV
That's the driving distance. It would take 1 day 18 hours to go from Lakeland, Florida to Mesquite, Nevada.
The flight distance (direct flight from Lakeland, FL to Mesquite, NV) is 1,957.92 mi.
2,304 mi = 3.22 kms