Miles between Lafayette, IN and Sikeston, MO

There are
359 mi
from Lafayette, IN to Sikeston, MO

That's the driving distance. It would take 6 hours 42 mins to go from Lafayette, Indiana to Sikeston, Missouri.

The flight distance (direct flight from Lafayette, IN to Sikeston, MO) is 285.01 mi.

359 mi = 577.25 kms