There are
1,856 mi
from La Mesa, CA to Shiloh, IL
That's the driving distance. It would take 1 day 8 hours to go from La Mesa, California to Shiloh, Illinois.
The flight distance (direct flight from La Mesa, CA to Shiloh, IL) is 1,568.08 mi.
1,856 mi = 2,986.89 kms