There are
2,085 mi
from La Mesa, CA to Evanston, IL
That's the driving distance. It would take 1 day 12 hours to go from La Mesa, California to Evanston, Illinois.
The flight distance (direct flight from La Mesa, CA to Evanston, IL) is 1,722.11 mi.
2,085 mi = 3,354.67 kms