There are
2,056 mi
from La Mesa, CA to Downers Grove, IL
That's the driving distance. It would take 1 day 12 hours to go from La Mesa, California to Downers Grove, Illinois.
The flight distance (direct flight from La Mesa, CA to Downers Grove, IL) is 1,702.61 mi.
2,056 mi = 3,309.37 kms