Miles between Knoxville, TN and Tupelo, MS

There are
348 mi
from Knoxville, TN to Tupelo, MS

That's the driving distance. It would take 6 hours 51 mins to go from Knoxville, Tennessee to Tupelo, Mississippi.

The flight distance (direct flight from Knoxville, TN to Tupelo, MS) is 294.78 mi.

348 mi = 560.66 kms