Miles between Knoxville, TN and St Louis, MO

There are
485 mi
from Knoxville, TN to St Louis, MO

That's the driving distance. It would take 8 hours 54 mins to go from Knoxville, Tennessee to St Louis, Missouri.

The flight distance (direct flight from Knoxville, TN to St Louis, MO) is 391.08 mi.

485 mi = 780.92 kms