Miles between Knoxville, TN and St Charles, MO

There are
506 mi
from Knoxville, TN to St Charles, MO

That's the driving distance. It would take 9 hours 21 mins to go from Knoxville, Tennessee to St Charles, Missouri.

The flight distance (direct flight from Knoxville, TN to St Charles, MO) is 411.13 mi.

506 mi = 814.82 kms