Miles between Knoxville, TN and Simpsonville, SC

There are
181 mi
from Knoxville, TN to Simpsonville, SC

That's the driving distance. It would take 3 hours 49 mins to go from Knoxville, Tennessee to Simpsonville, South Carolina.

The flight distance (direct flight from Knoxville, TN to Simpsonville, SC) is 126.35 mi.

181 mi = 291.89 kms