There are
684 mi
from Knoxville, TN to Sayreville, NJ
That's the driving distance. It would take 12 hours 57 mins to go from Knoxville, Tennessee to Sayreville, New Jersey.
The flight distance (direct flight from Knoxville, TN to Sayreville, NJ) is 604.44 mi.
684 mi = 1,101.17 kms