There are
2,496 mi
from Knoxville, TN to San Rafael, CA
That's the driving distance. It would take 1 day 20 hours to go from Knoxville, Tennessee to San Rafael, California.
The flight distance (direct flight from Knoxville, TN to San Rafael, CA) is 2,120.74 mi.
2,496 mi = 3.22 kms