Miles between Knoxville, TN and Port Orange, FL

There are
646 mi
from Knoxville, TN to Port Orange, FL

That's the driving distance. It would take 12 hours 3 mins to go from Knoxville, Tennessee to Port Orange, Florida.

The flight distance (direct flight from Knoxville, TN to Port Orange, FL) is 501.14 mi.

646 mi = 1,038.85 kms