Miles between Knoxville, TN and Picayune, MS

There are
550 mi
from Knoxville, TN to Picayune, MS

That's the driving distance. It would take 10 hours 4 mins to go from Knoxville, Tennessee to Picayune, Mississippi.

The flight distance (direct flight from Knoxville, TN to Picayune, MS) is 501.54 mi.

550 mi = 885.54 kms