There are
378 mi
from Knoxville, TN to Pataskala, OH
That's the driving distance. It would take 7 hours 11 mins to go from Knoxville, Tennessee to Pataskala, Ohio.
The flight distance (direct flight from Knoxville, TN to Pataskala, OH) is 286.93 mi.
378 mi = 608.51 kms