Miles between Knoxville, TN and New Castle, IN

There are
353 mi
from Knoxville, TN to New Castle, IN

That's the driving distance. It would take 6 hours 46 mins to go from Knoxville, Tennessee to New Castle, Indiana.

The flight distance (direct flight from Knoxville, TN to New Castle, IN) is 285.32 mi.

353 mi = 568.74 kms