There are
2,167 mi
from Knoxville, TN to Murrieta, CA
That's the driving distance. It would take 1 day 13 hours to go from Knoxville, Tennessee to Murrieta, California.
The flight distance (direct flight from Knoxville, TN to Murrieta, CA) is 1,888.07 mi.
2,167 mi = 3,487.33 kms