Miles between Knoxville, TN and Mt Pleasant, SC

There are
377 mi
from Knoxville, TN to Mt Pleasant, SC

That's the driving distance. It would take 7 hours 13 mins to go from Knoxville, Tennessee to Mt Pleasant, South Carolina.

The flight distance (direct flight from Knoxville, TN to Mt Pleasant, SC) is 318.40 mi.

377 mi = 606.13 kms