Miles between Knoxville, TN and Middletown, OH

There are
288 mi
from Knoxville, TN to Middletown, OH

That's the driving distance. It would take 5 hours 25 mins to go from Knoxville, Tennessee to Middletown, Ohio.

The flight distance (direct flight from Knoxville, TN to Middletown, OH) is 246.97 mi.

288 mi = 462.83 kms