There are
2,335 mi
from Knoxville, TN to Mendota, CA
That's the driving distance. It would take 1 day 16 hours to go from Knoxville, Tennessee to Mendota, California.
The flight distance (direct flight from Knoxville, TN to Mendota, CA) is 2,017.20 mi.
2,335 mi = 3,757.33 kms