Miles between Knoxville, TN and Madison, AL

There are
221 mi
from Knoxville, TN to Madison, AL

That's the driving distance. It would take 4 hours 16 mins to go from Knoxville, Tennessee to Madison, Alabama.

The flight distance (direct flight from Knoxville, TN to Madison, AL) is 181.65 mi.

221 mi = 356.40 kms