Miles between Knoxville, TN and Lexington, SC

There are
259 mi
from Knoxville, TN to Lexington, SC

That's the driving distance. It would take 5 hours 9 mins to go from Knoxville, Tennessee to Lexington, South Carolina.

The flight distance (direct flight from Knoxville, TN to Lexington, SC) is 204.43 mi.

259 mi = 417.48 kms