There are
1,522 mi
from Knoxville, TN to Las Cruces, NM
That's the driving distance. It would take 1 day 2 hours to go from Knoxville, Tennessee to Las Cruces, New Mexico.
The flight distance (direct flight from Knoxville, TN to Las Cruces, NM) is 1,327.10 mi.
1,522 mi = 1.61 kms